Integrin Alpha2b Antikörper (FITC)

Produktnummer ABIN119841

Dieser Anti-Integrin Alpha2b Antikörper ist ein Ratte Monoklonal Antikörper zur Detektion von Integrin Alpha2b in FACS. Geeignet für Maus. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Integrin Alpha2b Antikörper (FITC) (ABIN119841)

Target: Integrin Alpha2b (CD41)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Integrin Alpha2b Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: MWReg30

Produktdetails anti-Integrin Alpha2b Antikörper (FITC)

Spezifität: This antibody recognises the integrin alpha IIb subunit CD41.

Aufreinigung: Protein G affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: use 10 μL of neat - 1/10 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo . We recommend the use of ABIN119839 for use in functional studies.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide and 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-Integrin Alpha2b Antikörper (FITC) (ABIN119841)

Zanzinger, Schellack, Nausch, Cerwenka: "Regulation of triggering receptor expressed on myeloid cells 1 expression on mouse inflammatory monocytes." in: Immunology, Vol. 128, Issue 2, pp. 185-95, (2009) (PubMed).

Larson, Watson: "Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3." in: Blood, Vol. 108, Issue 5, pp. 1509-14, (2006) (PubMed).

Details zu Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: CD41 / ITGA2B

Hintergrund: CD41 is expressed on platelets and megakaryocytes and forms a heterodimer with CD61. CD41/CD61 is important for platelet adhesion and aggregation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

Gen-ID: 16399

NCBI Accession: NP_034705

UniProt: Q9QUM0

Pathways: Integrin Complex